The complement system acts as a first line of defense and promotes organism homeostasis by modulating the fates of diverse physiological processes.Multiple copies of component genes have been previously identified in fish, suggesting a key swish supreme glide track white role for this system in aquatic organisms.Herein, we confirm the presence of t
Abstract The tumor microenvironment (TME) is essential for immune escape by tumor cells.It plays essential roles in tumor development and metastasis.The clinical outcomes of tumors are often closely related to individual differences in the patient TME.Therefore, reprogramming TME cells and their intercellular communication is an attractive and prom
Abstract NLRP3 induces caspase-1-dependent pyroptotic cell death to drive inflammation.Aberrant activity of NLRP3 occurs in many human diseases.NLRP3 activation induces ASC polymerization into a single, micron-scale perinuclear punctum.Higher resolution imaging of this signaling platform is needed to understand how it induces pyroptosis.Here, we ap
Our modern cities are resource sinks designed on the current linear economic model which recovers very little of the original input.As the current model is not sustainable, a viable solution is to recover and reuse parts of the input.In this context, resource recovery using nature-based solutions (NBS) is gaining popularity worldwide.In this specif
Cyber-physical systems (CPSs) have become vital to network communication.The CPS combines numerous interconnected computing resources, networking units, and physical processes to monitor the activities of computing devices.The perception layer in the CPS is employed to gather data from read more the physical surroundings.Still, the interconnection